The Jiaxing Birth Cohort is an unique resource to explore prenatal risk factors, early life feeding practice and growth pattern/adiposity in Chinese children. In addition, the Jiaxing Birth Cohort enables us to have a contemporary view of change in maternal and child characteristics and their impact on child growth in the past decade in this region.

  • General Information of Study
    • Overview
      Name The Jiaxing Birth Cohort (JBC)
      Project Number CCC2018010401
      Website None
      Investigators
      Duo Li
      Institutions Nutrition and health institute, Qingdao University
      Contacts
      Huang Tao
      Funding National Natural Science Foundation of China (NSFC: 81273054); and by the Ph.D. Programs Foundation of Ministry of Education of China (20120101110107).
      Objectives The Jiaxing Birth Cohort is an unique resource to explore prenatal risk factors, early life feeding practice and growth pattern/adiposity in Chinese children. In addition, the Jiaxing Birth Cohort enables us to have a contemporary view of change in maternal and child characteristics and their impact on child growth in the past decade in this region.
      Start Date 1999
      End Date 2013
    • Study Design
      Number of Participants A total of 338 413 live mother-child pairs registered at local clinics, and were enrolled in the Jiaxing Birth Cohort. Among the 338 413 children, there were 332 532 singletons, 2883 pairs of twins (n = 5766), 37 pairs of triplets (n = 111), and 1 pair of quadruplets (n = 4).
      Age Range Women aged 18+.
      Geographic Distribution Jiaxing
      General Information of Study Design and Sample Methods Hospital based cohort
      Inclusion Criteria None
      Exclusion Criteria None
    • Other Information
      Key Achievements None
      Marker Papers 1) "Maternal Blood Pressure Rise During Pregnancy and Offspring Obesity Risk at 4 to 7 Years Old: The Jiaxing Birth Cohort.Zheng JS, Liu H, Ong KK, Huang T, Guan Y, Huang Y, Yang B, Wang F, Li D. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4315-4322. doi: 10.1210/jc.2017-01500.
      2) Increased pre-school overweight and obesity prevalence between 2004 and 2013 is associated with appetite, eating frequency and supportive facilities: the Jiaxing Birth Cohort in China. Liu H, Zheng JS, Li J, Chen Y, Zhao W, Huang T, Yang B, Li D. Asia Pac J Clin Nutr. 2017;26(5):881-887. doi: 10.6133/apjcn.072017.05. PMID: 28802298 Free Article
      3) Age of Complementary Foods Introduction and Risk of Anemia in Children Aged 4-6 years: A Prospective Birth Cohort in China. Wang F, Liu H, Wan Y, Li J, Chen Y, Zheng J, Huang T, Li D. Sci Rep. 2017 Mar 23;7:44726. doi: 10.1038/srep44726. PMID: 28333130 Free PMC Article
      4) Cohort Profile: The Jiaxing Birth Cohort in China. Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Int J Epidemiol. 2017 Oct 1;46(5):1382-1382g. doi: 10.1093/ije/dyw203. No abstract available. PMID: 27940484
      5) Sleep Duration and Overweight/Obesity in Preschool-Aged Children: A Prospective Study of up to 48,922 Children of the Jiaxing Birth Cohort. Wang F, Liu H, Wan Y, Li J, Chen Y, Zheng J, Huang T, Li D. Sleep. 2016 Nov 1;39(11):2013-2019. PMID: 27568808 Free PMC Article
      6) Prolonged Exclusive Breastfeeding Duration Is Positively Associated with Risk of Anemia in Infants Aged 12 Months. Wang F, Liu H, Wan Y, Li J, Chen Y, Zheng J, Huang T, Li D. J Nutr. 2016 Sep;146(9):1707-13. doi: 10.3945/jn.116.232967. Epub 2016 Aug 3. PMID: 27489010 Free Article
      7) Pre-conceptional intake of folic acid supplements is inversely associated with risk of preterm birth and small-for-gestational-age birth: a prospective cohort study. Zheng JS, Guan Y, Zhao Y, Zhao W, Tang X, Chen H, Xu M, Wu L, Zhu S, Liu H, Huang T, Li D. Br J Nutr. 2016 Feb 14;115(3):509-16. doi: 10.1017/S0007114515004663. Epub 2015 Dec 14.
      8) Complementary feeding and childhood adiposity in preschool-aged children in a large Chinese cohort. Zheng JS, Liu H, Zhao YM, Li J, Chen Y, Zhu S, Chen H, Huang T, Li D. J Pediatr. 2015 Feb;166(2):326-31.e2. doi: 10.1016/j.jpeds.2014.11.010. Epub 2014 Dec 6.
      9) Exclusive breastfeeding is inversely associated with risk of childhood overweight in a large Chinese cohort. Zheng JS, Liu H, Li J, Chen Y, Wei C, Shen G, Zhu S, Chen H, Zhao YM, Huang T, Li D. J Nutr. 2014 Sep;144(9):1454-9. doi: 10.3945/jn.114.193664. Epub 2014 Jul 9."
      Strength The JBC is a birth cohort with large sample size in the eastern of China. The data resource is rich.
      Weakness No blood sample.