Epidemiology of eye diseases in rural China. To determine the prevalence and incidence of ocular diseases; prevalence of blindness and visual impairment; influence factors of ocular diseases and progression.

  • General Information of Study
    • Overview
      Name Handan Eye study
      Project Number CCC2018051002
      Website N.A.
      Investigators
      Ningli Wang
      Institutions Beijing Tongren Hospital, Capital Medical University
      Contacts
      Jie Hao
      Funding Grant 2007CB512201 from the Ministry of Science and Technology of the People’s Republic of China
      Objectives Epidemiology of eye diseases in rural China.
      To determine the prevalence and incidence of ocular diseases; prevalence of blindness and visual impairment; influence factors of ocular diseases and progression.
      Start Date October,2006
      End Date October, 2013
    • Study Design
      Number of Participants 6830
      Age Range >=30 years
      Geographic Distribution Yongnian county, Handan city, Hebei province
      General Information of Study Design and Sample Methods clusterd randomzied
      Inclusion Criteria Handan residents aged 30 years or more, we refered The bluemontain study in Austrialia
      Exclusion Criteria People having mental diseases or severe physical diseases, that could not cooperate
    • Other Information
      Key Achievements 1.determine the agespecific prevalence of blindness, visual impairment, and ocular disease among the rural population 30 years or older living in Yongnian County.
      2.determine the primary causes of blindness and visual impairment.
      3.identify risk factors for the presence of these conditions.
      Marker Papers 1.Prevalence of age-related macular degeneration in a rural Chinese population: the Handan Eye Study. Yang K, Liang YB, Gao LQ, Peng Y, Shen R, Duan XR, Friedman DS, Sun LP, Mitchell P, Wang NL, Wong TY, Wang JJ. Ophthalmology. 2011 Jul;118(7):1395-401. doi: 10.1016/j.ophtha.2010.12.030. Epub 2011 Mar 27.
      2.Prevalence and causes of amblyopia in a rural adult population of Chinese the Handan Eye Study. Wang Y, Liang YB, Sun LP, Duan XR, Yuan RZ, Wong TY, Yi P, Friedman DS, Wang NL, Wang JJ. Ophthalmology. 2011 Feb;118(2):279-83. doi: 10.1016/j.ophtha.2010.05.026. Epub 2010 Sep 24.
      3.Normal macular thickness measurements using optical coherence tomography in healthy eyes of adult Chinese persons: the Handan Eye Study.
      4.Retinopathy in persons without diabetes: the Handan Eye Study. Peng XY, Wang FH, Liang YB, Wang JJ, Sun LP, Peng Y, Friedman DS, Liew G, Wang NL, Wong TY. Ophthalmology. 2010 Mar;117(3):531-7, 537.e1-2. doi: 10.1016/j.ophtha.2009.07.045. Epub 2009 Dec 24.
      5.Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. Wang FH, Liang YB, Zhang F, Wang JJ, Wei WB, Tao QS, Sun LP, Friedman DS, Wang NL, Wong TY. Ophthalmology. 2009 Mar;116(3):461-7. doi: 10.1016/j.ophtha.2008.10.003. Epub 2009 Jan 24.
      Strength rural area, comprehensive measurement on opthalmology
      Weakness Image reading will cost more time than planned, follow-up analyses are currently postponed.